Madonna has blasted "ridiculous" claims that Adele is "too fat".
Chanel designer Karl Lagerfeld accused the 'Someone Like You' singer of being overweight last month, but Madonna, 53, believes Adele's clothes size is completely irrelevant.
She said: "That's horrible. That's ridiculous, that's just the most ridiculous thing I've ever heard.
"I don't like it when anybody says anything bad about anyone - I don't like it. Adele's a great talent and how much she weighs has nothing to do with it."
Discussing the deaths of Amy Winehouse and Whitney Houston- who both publicly battled problems with drink and drugs - Madonna admits she finds it hard to get her head around such a waste of talent.
She told The Sun: "I was hit by this shocking sense of disbelief - especially with Whitney Houston.
"It had not been a secret, the struggles Amy had been through - both brilliant, brilliant artists and obviously both huge losses.
"But when these things happen, I'm always shocked by the first thing you say - 'It's such a loss' - which doesn't quite cover it. Then you reflect and you think, 'How did it happen? How did the people around them allow it to happen?'"
She continued: "One thing I was struck by with Whitney Houston is I remember she sort of came out as a singer around the same time I did. I remember looking at her singing and hearing people talk about her, and just thinking, 'Oh my God. She's such a beautiful woman and my God, what an incredible voice. I wish I could sing like that.'
"I just remember being extremely envious of her and also touched by her innocence.
"I was struck by that - how well she started and where she ended up and the tragedy of it."