Alberta Ferretti has designed 30 pieces for Macy's Impulse contemporary department.
The Italian designer follows in the footsteps of Matthew Williamson, Giambattista Valli and Karl Lagerfeld in creating a collection for the US store and said she wanted to evoke the spirit of the Amalfi Coast in her designs.
She told WWD: "The collection I created is fresh and bright, featuring light summer clothing that evokes the spirit of my beautiful country and is at the same time true to my style."
The designs, which include feminine dresses, peasant blouses, garden-party looks, oversize and abstract floral prints and knitwear, will be sold exclusively at the store for 10 weeks from April 17.
Macy's revealed they chose Alberta as their latest designer because of her international appeal.
Jeff Gennette, Macy's chief merchandising officer said: "Alberta Ferretti's thriving business, international appeal and modern aesthetic enticed us to collaborate with her."
Martine Reardon, executive vice president of marketing added: "She's very top of mind today. "She just had two very successful shows. She appeals to an international consumer as well as an American consumer, and her fabrications are very soft, very feminine, chiffonlike, drapy, comfortable and really pretty, yet they look very elegant."