Man City's quest for European glory resumes on Tuesday when they travel to Switzerland to face Basel in the Champions League last-16.

Basel v Manchester City

Basel v Manchester City

Pep Guardiola's men are on course for an unprecedented quadruple as they continue to run away with the Premier League, opening up a 16-point lead at the top of the table with Saturday's 5-1 win over Leicester City, while they remain in contention in the Carabao Cup and FA Cup.

Having proven they are the best team in England this season, conquering Europe is the next step for the Citizens and they start as heavy favourites to take care of Basel having won five out of their six group stage matches on route to the knockout rounds.

While City come in to the game having won five of their last six matches in all competitions, Basel have produced a mixed bag since the resumption of the Swiss Super League following the winter break, losing at home to Lugano before bouncing back at the weekend at FC Thun.

The RotBlau have also been dealt a blow on the injury front as they wait to see whether they will have midfielder Luca Zuffi and defender Eder Balanta available due to respective foot and thigh injuries.

Basel can at least take some comfort from their excellent home record against English opposition in Europe, winning four of the last five matches at St. Jakob-Park, including beating Manchester United in this season's group stages.

City's record in the Champions League knockout stages will also provide the Swiss with a bit of belief, the Manchester club only making it beyond the last-16 once and winning just one out of six knockout games away from the Etihad Stadium.

This is a much-changed City side though and Guardiola has been handed a boost by the rapid recovery of Leroy Sane from an ankle injury, the German providing himself fit enough to be included in the travelling party.

Fabian Delph and David Silva also look set to feature having played a full part in training on Monday but doubts remain over the fitness of record signing Aymeric Laporte.