Jose Mourinho says out of his injured stars, only Phil Jones is likely to recover in time to face Tottenham on Saturday.
Jones was on the bench as Manchester United booked their place in the quarter-finals of the Carabao Cup with a 2-0 win at Swansea, and could be in line to start against Spurs if need be.
Michael Carrick, Marouane Fellaini and Paul Pogba all remain out through injury, as does Zlatan Ibrahimovic, Marcos Rojo and Eric Bailly and none of them are likely to return this weekend.
"I think Jones will be because today he was on the bench and if I needed him he was ready," Mourinho said when asked who could return against Spurs. "Apart from that I have no news."
In a bid to keep his squad fit Mourinho made seven changes for the tie, with only Jesse Lingard, Chris Smalling, Ander Herrera and Anthony Martial remaining from the side beaten by Huddersfield, and the 54-year-old was particularly pleased with the performances of 19-year-old defender Axel Tuanzebe and 20-year-old midfielder Scott McTominay.
"I think they did both well," he added. "I'd say Scott probably very well because he was really comfortable and strong in midfield.
"Axel I think he started a little bit shaky but then he got stability and had also a good performance."