Winston Reid has been ruled out of West Ham's weekend clash with Stoke City due to a suspension.
The New Zealander picked up his fifth booking of the season in the Hammers' 0-0 midweek derby clash with Arsenal, which saw David Moyes' men pick up their second consecutive clean sheet to ease any early pressure on the recently appointed boss.
Either James Collins or Declan Rice are likely to deputise for Reid, with midfielder Edmilson Fernandes a possibility to return to the squad following an ankle injury.
Moyes also used his pre-match press conference to praise midfielder Mark Noble, who is set to make his 300th Premier League appearance for his boyhood side against the Potters this weekend.
"He's played well for us, he's captain and is making sure all the players are doing the right thing," he said. "It's a great achievement for him and I hope he continues to do it for us."
Otherwise, it is likely to be the same squad that faced Arsenal with Moyes steadily improving the beleaguered London club.